Moral implications in the methods and applications of GM animals

Document Type : Original Article

Authors

Islamic institute for culture and thought

Abstract

Genetically modified animals, due to their multiple and unique uses, are of the most important achievements in biotechnology. However, as they have feelings and perception the production of these animals should be done within a specific normative framework. The most important ethical approaches in this field can be regarded under three headings of free use, absolute prohibition and conditional use. The axe of ethical considerations in the latter approach is considering the two elements of waste and teasing animals (physical/psychological) in the process of genetic engineering on the one hand and to ensure a rational balance between said elements and rational objectives of genetically engineering on the other hand. The presence of the elements of waste and teasing animals can be investigated in two levels of production methods and applications of transgenic animals. In the level of methods, since we are to admit the presence of both elements waste and teasing during the genetic transferring process, the emphasis must be put on the need to use techniques having waste and teasing as less as possible. In the applications level as a general approach the laboratory and animal welfare conditions is considered to be important and also in certain teasing applications like disease models, scientific models and xenotransplantation, the use of effective methods of euthanasia is recommended.

Keywords


  1. ابن‌بابویه قمی (صدوق)، ابوجعفر محمدبن‌علی؛ الهدایة؛ قم: مؤسسه امام هادى†، 1418ق.
  2. اصفهانی (فاضل هندی)، محمدبن‌حسن؛ کشف اللثام عن قواعد الأحکام؛ قم: جامعه مدرسین حوزه علمیه، 1382.
  3. تمیمی مغربی، نعمان‌بن‌محمدبن‌منصور؛ دعائم الإسلام؛ چ2، قم: مؤسسه آل‌البیت‰، 1385ق.
  4. جوادی، محسن و اصغر مسعودی؛ «حقوق حیوانات ازمنظر اسلام»؛ پژوهش‌های اخلاقی، ش14، زمستان 1392.
  5. حرّ عاملی، محمدبن‌حسن؛ وسائل الشیع‍ة؛ چ2، قم: مؤسسه آل‌البیت لإحیاء التراث، 1414ق.
  6. حلّی، ابن‌ادریس؛ السرائر؛ ج2، چ2، قم: جامعه مدرسین حوزه علمیه، 1410ق.
  7. سلمانی ایزدی، ناصر و الهام صالحی؛ «حقوق حیوانات ازمنظر فقه و قانون»؛ مطالعات علوم سیاسی، حقوق و فقه، ش1، بهار 1396.
  8. شهبازی، آرامش؛ «حقوق حیوانات: تأملی در نظریه و رویّه»؛ پژوهش حقوق عمومی، ش36، بهار 1391.
  9. طباطبایی، سیدمحمدحسین؛ المیزان فی تفسیر القرآن؛ قم: دفتر انتشارات اسلامی جامعه مدرسین حوزه علمیه قم، 1417ق.
  10. طوسی، محمدبن‌حسن؛ التبیان فی تفسیر القران؛ تهران: ذوی‌القربی، 1388.
  11. عاملی (شهید ثانی)، زین‌الدین‌بن‌علی؛ الروضة البهیة فی شرح اللمعة الدمشقیة؛ ج1، چ2، قم: دارالتفسیر، 1381.
  12. ـــــ ؛ مسالک الأفهام فی شرح شرائع الإسلام؛ قم: بنیاد معارف اسلامی، 1383.
  13. کاظمی، عبدالحسن و دیگران؛ «حقوق حیوانات و تحقیقات زیست پزشکی»؛ اخلاق پزشکی، ش15، بهار 1390.
  14. کلینی، محمدبن‌یعقوب؛ الکافی؛ چ3، تهران: دار الکتب الإسلامیة، 1388ق.
  15. متقی هندی، علاء­الدین‌علی­بن­حسام؛ کنز‌العمّال فی سنن الأقوال و الأفعال؛ چ2، بیروت: انتشارات مؤسسة الرسالة، 1409ق.
  16. مجلسی، محمدباقر؛ بحارالأنوار؛ بیروت: مؤسسة وفاء، 1403ق.
  17. منوچهری، مهدی و دیگران؛ «حقوق حیوانات در تحقیقات بیوتکنولوژی و بیومدیکال»؛ اخلاق پزشکی، ش8، تابستان 1388.
  18. نجفی، محمدحسن؛ جواهرالکلام فی شرح الشرائع الإسلام؛ قم: کتابفروشی الإسلامیة، 1386.
    1. Aaltola, Elisa; Animal Suffering: Philosophy and Culture; Palgrave Mcmiillan, 2012.
    2. Ackerknecht, Erwin H. and Lisa Haushofer; A Short History of Medicine; John Hopkins University Press, 2016.
    3. Benz ـ Schwarzburg, Judith & Arianna Ferrari; ‘Super ـ Muscly Pigs’; Issues In Science And Technology 32, No. 3 (Spring 2016), At <Http://Issues.Org/32 ـ 3/Perspective ـ Super ـ Muscly ـ Pigs.
    4. Broughton, ‎ Janet  and John Carriero  (eds.); A Companion to Descartes; Wiley-Blackwel, 2010.
    5. Blanco, Jeffrey and Savan Ratanpara; Transgenic Animals; Worcester Polytechnic Institute, 2012.
    6. Bloom, Floyd E.; Quantitative Neuropathology in Alzheimer's Mouse Models, "Synaptic Plasticity and the Mechanism of Alzheimer's Disease" edited by Dennis J. Selkoe, Antoine Triller, Springer, 2008.
    7. Broom, Donald M.; Sentience and Animal Welfare, 2014.
    8. Bruce, Donald; Engineering Genesis: Ethics of Genetic Engineering in Non ـ human Species; Routledge, 2013.
    9. Bynum, William F. et al (eds.); Dictionary of the History of Science; Princeton University Press, 1981.
    10. Camara, D. Et Al.; Transgenic and Cloned Animals: Ethical Problems, Perugia; April 2008.
    11. Conn, Michael (ed.); Sourcebook of Models for Biomedical Research; Humana Press, 2008.
    12. Dol, Marcel et al (eds.); Recognizing the Intrinsic Value of Animals: Beyond Animal Welfare, 2005.
    13. Forsman, Birgitta; Animal and Human Welfare, Ethical Aspect Of The Use of Transgenic Animals, 1998.
    14. Francione, Gary L.; Animals as Persons: Essays on the Abolition of Animal Exploitation; 2009.
    15. Franco, Nuno H. and I Anna Solsson, Killing animals as a necessary evil? The case of animal research, 1998.
    16. Gibbons, John, H., Patenting Life, New Developments in Biotechnology, 1989.
    17. Gordon, JW Et Al., 'Integration and Stable Germ Line Transmission of Genes Injected Into Mouse Pronuclear', Science 214, 1981, 1244 ـ 1246.
    18. Hills, Alison, Do Animals Have Rights?, UK: Icon Books, 2005.
    19. Kac, Eduardo,Telepresence & Bio Art: Networking Humans, Rabbits, & Robots, The University of Michigan Press, 2008.
    20. Kaiser, Matthias, 2003 .
    21. Kaliste, Eila (ed.), The Welfare of Laboratory Animals, Springer, 2007.
    22. Kazez, Jean, Animalkind: What We Owe To Animals,2009
    23. Khatib, Hasan, Molecular and Quantitative Animal Genetics, 2015, Wiley Blackwell.
    24. King, Elaine A. and Gail Levin, Ethics and the Visual Arts, New York, Allworth Press, 2006.
    25. Lauritzen, Paul, Cloning and the Future of Human Embryo Research, 2001.
    26. Marius, Turda (Ed.), Crafting Humans: From Genesis To Eugenics And Beyond, P.100; Lodge, Julia, Gene Cloning,2013
    27. Martin Bazinet & Maceo Braxton, 'Transgenic Animals', Worcester Polytechnic Institute, August 24, 2005.
    28. Mary Buy, 'Transgenic Animals', Canadian Council on Animal Care. University Of. Calgary, Spring, 1997, At <Http:// People.Ucalgary.Ca/~Browder/ Transgenic. Html >.
    29. Matthew and Joanna Brosius, Transgenic Animals, 2006.
    30. Matthew Bradley & Joanna Brosius, 'Transgenic Animals', Worcester Polytechnic Institute, August 23, 2006.
    31. Mclean, Sheila A. M., First Do No Harm: Law, Ethics And Healthcare, 2016.
    32. McLean, Sheila and Laura Williamson, Xenotransplantation: Law and Ethics, Ashgate , 2005.
    33. National Research Council, ‎Division on Earth and Life Studies, ‎Board on Life Sciences, Animal Biotechnology: Science Based Concerns, 2002
    34. Paul Cupido, Transgenic Animals, 2011
    35. Perry, Anthony Et Al., 'Mammalian Transgenesis By Lntracytoplasmic Sperm Injection', SCIENCE 284, 14 MAY 1999, P. 1180.
    36. Phillips,Mary T. and Jeri A. Sechze, ,Animal Research and Ethical Conflict: An Analysis of the Scientific, 2012.
    37. Rasko, John and Gabrielle O'Sullivan, Rachel Ankeny, The Ethics of Inheritable Genetic Modification: A Dividing Line? , Springer 2006.
    38. Rollin, Bernard E (1996) Bad Ethics, Good Ethics, and The Genetic Engineering of Animals In Agriculture. 3rd Ed. Vol. 74. Journal of Animal Science, 1996. 535 ـ 41.
    39. Rownalds, Mark, Animal Rights: Moral Theory and Practice, 2016.
    40. Singer, peter, Animal Liberation, Random House Press, 2015
    41. Singer, peter, Practical Ethics, Cambridge University Press, 2011.
    42. Smith, Kevin R., ‘Animal Genetic Manipulation: A Utilitarian Response’, 2002.
    43. Sunstein, Cass R. And Martha C. Nussbaum, Animal Rights Current Debates And New Directions, Oxford University Press, 2004
    44. Sunstein, Cass R. and Martha C. Nussbaum, Animal Rights: Current Debates and New Directions, 2001.
    45. Susan B. Harper, 'How Transgenics Are Produced', FDA Veterinarian Newsletter. Vol 14. FDA U.S. Department of Health and Human Services, 1999.
    46. Susan Jean Armstrong and Richard George Botzler (eds.), The Animal Ethics Reader, Routledge, 2003.
    47. Verhoog, Henk, Morality And Naturalness of Transgenic Animals, pp.1-4
    48. Vos, Ellen and Michelle Everson (ed.), Uncertain Risks Regulated, Routledge, 2009.
    49. Wong, Dominic, The ABCs of Gene Cloning, Springer, 2007.
    50. Franklin, Julian H.; Animal Rights and Moral Philosophy; Columbia University Press, 2006.